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oai:www.ideals.illinois.edu:2142/87630 2023-07-11 col_2142_5131 col_2142_25441 com_2142_5130 com_2142_25440 com_2142_14833

Silvia N.J.Moreno Ling, Yan 2015-09-28T16:21:38Z 2015-09-28T16:21:38Z 10000-01-01 2005 2005 In summary, this work provides information to understand the isoprenoid pathway in T. gondii by isolation and characterization of an important enzyme in the pathway, TgFGGPS. Identification of TgFGGPS as the molecular target of bisphosphonates in this work provides a key tool for rational-based drug design. In addition, this work represents a new approach to chemotherapy of toxoplasmosis with a group of safe and easy to prepare compounds. Made available in DSpace on 2015-09-28T16:21:38Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3199069.pdf: 2530011 bytes, checksum: 7b9444bfd2aca0cac867a7cbebde7f13 (MD5) Previous issue date: 2005 Embargo set by: Seth Robbins for item 88911 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 103 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2005. http://hdl.handle.net/2142/87630 (MiAaPQ)AAI3199069 eng Biology, Cell Farnesyl Pyrophosphate/geranylgeranyl Pyrophosphate Synthase of Toxoplasma Gondii: Its Role in the Parasite Isoprenoid Pathway and as a Target for Bisphosphonates text Veterinary Pathobiology Veterinary Pathobiology University of Illinois at Urbana-Champaign Dissertation Ph.D.