2026-09-18T19:13:15Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/98171 2023-07-11 col_2142_13007 col_2142_5131 com_2142_13006 com_2142_5130

Barbey, Aron K Barbey, Aron K Cohen, Neal J. Dilger, Ryan N. Jokela, Janet A. Zamroziewicz, Marta Karolina 2017-09-29T17:45:36Z 2017-09-29T17:45:36Z 2020-03-03T10:15:29Z 2017-06-21 2017-08 Nutritional cognitive neuroscience is an emerging interdisciplinary field of research that seeks to understand nutrition’s impact on cognition and brain health across the life span. While accumulating evidence indicates healthy cognitive aging is dependent upon both brain health and nutritional status, the relationship between nutrition, cognition, and brain structure and function remains to be elucidated. Methods that sensitively measure variability in nutritional status, cognition, and brain health are critical to clarifying the role of nutrition in healthy brain aging. This dissertation therefore employs a multidisciplinary approach that integrates cutting-edge techniques from nutritional epidemiology and cognitive neuroscience. The experiments presented herein define mediatory relationships between nutrition, cognition, and underlying brain structure and function in a sample of healthy, older adults. This research program investigates the role of nutrition in healthy brain aging, applying methods that examine: (i) specific nutrient biomarkers, and (ii) a broader profile of nutrient biomarker patterns. Chapters two through four investigate the role of individual nutrients on cognitive performance and identify specific brain regions whose structural integrity mediates this relationship. Chapters five through seven broaden the scope of this investigation to assess the role of nutrient biomarker patterns in cognition and to examine their influence of specific structural and functional brain networks. Taken together, the results of this research program suggest that specific nutrients and nutrient groups may slow or prevent aspects of age-related cognitive decline by influencing particular age-related changes in brain health. This line of research strives to elucidate the nature of healthy cognitive aging and ultimately inform clinical nutritional interventions for healthy brain aging. Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2019-08-01 The student, Marta Zamroziewicz, accepted the attached license on 2017-06-16 at 14:12. The student, Marta Zamroziewicz, submitted this Dissertation for approval on 2017-06-16 at 14:52. This Dissertation was approved for publication on 2017-06-21 at 14:35. DSpace SAF Submission Ingestion Package generated from Vireo submission #11232 on 2017-09-29 at 10:45:54 Made available in DSpace on 2017-09-29T17:45:36Z (GMT). No. of bitstreams: 3 ZAMROZIEWICZ-DISSERTATION-2017.pdf: 7431882 bytes, checksum: beb6e66a642551bfa4beeb44ad1cae8a (MD5) LICENSE.txt: 4215 bytes, checksum: 11b3319ebc6fe33aec5ce64aec12fc93 (MD5) Nutritional Neuroscience Permission.doc: 53760 bytes, checksum: dbcc773b2ee82555255a8ce5eb13d3a8 (MD5) Previous issue date: 2017-06-21 Embargo set by: Colleen Fallaw for item 103483 Lift date: 2019-09-29T17:48:06Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system Embargo set by: Seth Robbins for item 103483 Lift date: 2020-03-02T19:56:41Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system Embargo set by: Seth Robbins for item 103483 Lift date: 2020-03-02T19:59:52Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system Embargo set by: Seth Robbins for item 103483 Lift date: 2020-03-02T20:02:46Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system U of I Only Restriction Lifted for Item 103483 on 2020-03-03T10:15:29Z. application/pdf http://hdl.handle.net/2142/98171 en Copyright 2017 Marta Karolina Zamroziewicz Nutritional cognitive neuroscience Cognitive health Brain health Nutritional status A role for nutrition in healthy brain aging text text Neuroscience Program Neuroscience University of Illinois at Urbana-Champaign Dissertation Ph.D.