University of Illinois Urbana-Champaign

Brain anatomy: investigations of the effects of aging, fitness, and arterial stiffness

Fletcher, Mark Allen

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https://hdl.handle.net/2142/98210

Description

Title
Brain anatomy: investigations of the effects of aging, fitness, and arterial stiffness
Author(s)
Fletcher, Mark Allen
Issue Date
2017-05-19
Director of Research (if dissertation) or Advisor (if thesis)
  • Fabiani, Monica
  • Gratton, Gabriele
Doctoral Committee Chair(s)
  • Fabiani, Monica
  • Gratton, Gabriele
Committee Member(s)
  • Sutton, Brad
  • Dye, Matthew
Department of Study
Neuroscience Program
Discipline
Neuroscience
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
  • Neuroscience
  • Anatomy
  • Aging
  • Cerebrovascular
  • Fletcher
  • Fitness
Abstract
This work explores the mechanisms and lifestyle modifiers of brain anatomy throughout the aging process. First, a thorough review of the mechanisms of fitness on brain anatomy is presented. Next, a study examining the effects of aging and fitness on cortical and subcortical brain anatomy in a group of older adults (55-87 years old) is presented. We examine the degree to which cortical, subcortical, and global volumes are sensitive to both age and fitness. Lastly, the effect of cerebrovascular stiffness on the anatomical difference between and within individual subjects is explored across the lifespan (18-75 years old).
Graduation Semester
2017-08
Type of Resource
text
Permalink
http://hdl.handle.net/2142/98210
Copyright and License Information
Copyright 2017 Mark Allen Fletcher

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Dissertations - Neuroscience
Graduate Dissertations and Theses at Illinois PRIMARY
Graduate Theses and Dissertations at Illinois