Sex differences on the effect of obesity on the morphology of the intestinal epithelium
Mei, Angelina; Zhou, Weinan; Davis, Elizabeth A.; Dailey, Megan J.
Loading…
Permalink
https://hdl.handle.net/2142/99762
Description
Title
Sex differences on the effect of obesity on the morphology of the intestinal epithelium
Author(s)
Mei, Angelina
Zhou, Weinan
Davis, Elizabeth A.
Dailey, Megan J.
Issue Date
2018-04
Keyword(s)
obesity
intestine
diet
sex differences
morphology
Abstract
It is known that obesity causes the morphology of lining of the small intestine, the epithelium, to change. It causes the villi, the finger like projections responsible for nutrient absorption, to be longer. It also causes the crypts, which contain the stem cells, to be deeper. The differences of morphology between male and female mice have not been previously studied. This project involves inducing obesity in mice using a high fat diet and then observing the effect on the length of the villi and crypts of in the small intestine. Results from this study can contribute to the understanding of the mechanisms of nutrient triggered cellular adaption of the intestine and can also provide insight to intestinal diseases.
Use this login method if you
don't
have an
@illinois.edu
email address.
(Oops, I do have one)
IDEALS migrated to a new platform on June 23, 2022. If you created
your account prior to this date, you will have to reset your password
using the forgot-password link below.
