Environmental Contaminants in the Lake Huron to Erie Corridor: Effects on Zebrafish
Author(s)
Baker, Tracie
Meyer, Danielle
Crofts, Emily
Shields, Jeremiah
Akemann, Camille
Baker, Bridget
Issue Date
2019-05-22
Keyword(s)
Great Lakes
fish
Abstract
Contaminants of emerging concern (CECs) and endocrine-disrupting chemicals (EDCs) include pharmaceutical, personal care, agricultural, and industrial byproducts that enter waterways via effluent, runoff, aging infrastructure, and inadequate wastewater treatment. The Detroit River is an Area of Concern, but the drinking water source for ~4 million people, hub of >30% of Michigan’s fishing effort, and home to vital habitats. Zebrafish are advantageous for such complex issues due to short generation times and large numbers of synchronously developing fish. We investigate early development or chronic exposure of zebrafish to Detroit River water and evaluate changes in embryonic development, behavior, reproductive capacity, sex ratio, offspring survival, transcriptome, and epigenome. We also analyze water samples in the Lake Huron to Erie corridor for CECs and EDCs, and then evaluate the same endpoints in zebrafish exposed to these chemicals at environmentally-relevant levels, either singly or in mixtures. This multi-pronged approach has implications for local human and fish health, water treatment/sewage infrastructure, remediation/restoration efforts, natural resource management, public education, and community revitalization.
Series/Report Name or Number
2019 Emerging Contaminants in the Environment Conference (ECEC19)
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