University of Illinois Urbana-Champaign

Preventing bacterial infection of implants for bone regeneration

Dewey, Marley

Content Files
Dewey_Marley.jpg

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https://hdl.handle.net/2142/109746

Description

Title
Preventing bacterial infection of implants for bone regeneration
Author(s)
Dewey, Marley
Contributor(s)
  • Collins, Alan
  • Harley, Brendan
Issue Date
2021
Keyword(s)
  • Bacterial Infection
  • Biomaterials
Date of Ingest
2021-04-12T22:32:12Z
Abstract
Bacterial infection during surgical operations is a challenge for many tissue engineering approaches for wound healing. One of the design principles of implants to replace missing, damaged, or diseased tissue is preventing the aggregation of bacteria on these. Bacteria present within a wound site can prevent healing and lead to further complications such as abscess formation and additional surgeries to remove the infected tissue. Additionally, some bacterial strains have demonstrated resistance to antibiotics, the typical method to eliminate bacteria. Here, pseudomonas aeruginosa bacteria (orange) adhere to a collagen-based biomaterial (blue) for regeneration of large missing segments of bone. Researchers are currently investigating methods to prevent bacterial adhesion on these biomaterials through the addition of natural manuka honey, which has been shown to disrupt even antibiotic-resistant bacteria.
Type of Resource
Image
Genre of Resource
Photograph
Language
eng
Permalink
http://hdl.handle.net/2142/109746
Copyright and License Information
Copyright 2021 Marley Dewey

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