A Rotational Study Of 6-apa

Mato, Sergio

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https://hdl.handle.net/2142/116902 Copy

Description

Title

A Rotational Study Of 6-apa

Author(s)

Mato, Sergio

Contributor(s)

• León, Iker
• Alonso, José L.
• Alonso, Elena R.
• Mata, Santiago

Issue Date

2022-06-20

Keyword(s)

Structure determination

Abstract

6-Aminopenicillanic acid (6-APA) is one of the essential intermediates in synthesizing semisynthetic and naturally occurring penicillins. We have transferred 6-APA into the gas phase using laser ablation techniques and characterized its conformational panorama using chirped-pulse Fourier transform microwave (LA-CP-FTMW) spectroscopy. The spectroscopic parameters derived from the spectrum analysis conclusively identify the existence of four conformers of 6-APA. The 14N nuclear quadrupole coupling constants have been analyzed, allowing an accurate structural determination. The observed structures correlate nicely with the biological function of 6-APA.

Publisher

International Symposium on Molecular Spectroscopy

Type of Resource

text

Genre of Resource

Conference Paper / Presentation

Language

eng

Handle URL

https://hdl.handle.net/2142/116902

DOI

https://doi.org/10.15278/isms.2022.MI11

Copyright and License Information

Copyright 2022 held by the authors

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