Physical fitness and cardiovascular function in multiple sclerosis

Platta, Matthew E.

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https://hdl.handle.net/2142/78550 Copy

Description

Title

Physical fitness and cardiovascular function in multiple sclerosis

Author(s)

Platta, Matthew E.

Issue Date

2015-04-30

Department of Study

Kinesiology & Community Health

Discipline

Kinesiology

Degree Granting Institution

University of Illinois at Urbana-Champaign

Degree Name

M.S.

Degree Level

Thesis

Keyword(s)

• multiples sclerosis
• exercise
• respiratory fitness
• muscular fitness
• fitness
• arterial function
• cardiovascular

Abstract

Multiple sclerosis (MS) is an immune-mediated neurodegenerative disease that affects the central nervous system. Cardiovascular function (CV) has been shown to be impaired in persons with MS which can lead to the development of comorbidities that can promote disability progression. Cardiorespiratory fitness (CRF) and, to a lesser extent, muscular fitness (MF) have been shown to improve CV function in healthy populations. This thesis examined the relationships between CRF, MF, and exercise presented by randomized controlled trials via meta-analysis. Then, the relationships between CRF, MF, and CV function in persons with MS was determined in order to determine targets for therapy that might improve CV function. Results suggest exercise training improved CRF and MF in RCTs of exercise training examining CRF and MF outcomes. Further, the results of this cross-sectional study indicate significant relationships exist between CRF, MF and CV function in persons with MS. These studies support the potential to improve physiological fitness through exercise training as a possible means to improve CV function in persons with MS. This might be accomplished through exercise training interventions involving aerobic and/or resistance exercise.

Graduation Semester

2015-5

Type of Resource

text

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http://hdl.handle.net/2142/78550

Copyright and License Information

Copyright 2015 Matthew Platta

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