The Influence of Beta-Carotene and Lycopene on Human Prostate Tumor Cells in Vitro and Human Prostate Tumors in Mice
Williams, Alexa W.
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https://hdl.handle.net/2142/83728
Description
Title
The Influence of Beta-Carotene and Lycopene on Human Prostate Tumor Cells in Vitro and Human Prostate Tumors in Mice
Author(s)
Williams, Alexa W.
Issue Date
1998
Doctoral Committee Chair(s)
John W. Erdman, Jr.
Department of Study
Food Science and Human Nutrition
Discipline
Food Science and Human Nutrition
Degree Granting Institution
University of Illinois at Urbana-Champaign
Degree Name
Ph.D.
Degree Level
Dissertation
Keyword(s)
Health Sciences, Oncology
Language
eng
Abstract
An overall goal of this research was to investigate the influence of tomatoes, BC and lycopene on prostate carcinogenesis under biologically relevant conditions. To this end, a novel approach for the delivery of carotenoids to cells in culture and a murine model were developed. There was no evidence from the athymic model that whole tomato or tomato extracts reduced the progression of advanced prostate cancer.
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